Author: Jung, Kwonil; Hu, Hui; Eyerly, Bryan; Lu, Zhongyan; Chepngeno, Juliet; Saif, Linda J.
Title: Pathogenicity of 2 Porcine Deltacoronavirus Strains in Gnotobiotic Pigs Cord-id: yi52fqmu Document date: 2015_4_25
ID: yi52fqmu
Snippet: To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21–120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.
Document: To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21–120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.
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