Author: Zahedipour, Fatemeh; Hosseini, Seyede Atefe; Sathyapalan, Thozhukat; Majeed, Muhammed; Jamialahmadi, Tannaz; Alâ€Rasadi, Khalid; Banach, Maciej; Sahebkar, Amirhossein
Title: Potential effects of curcumin in the treatment of COVIDâ€19 infection Cord-id: ykypuycq Document date: 2020_5_19
ID: ykypuycq
Snippet: Coronavirus disease 2019 (COVIDâ€19) outbreak is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARSâ€CoVâ€2) with considerable mortality worldwide. The main clinical manifestation of COVIDâ€19 is the presence of respiratory symptoms, but some patients develop severe cardiovascular and renal complications. There is an urgency to understand the mechanism by which this virus causes complications so as to develop treatment options. Curcumin, a natural polyphenoli
Document: Coronavirus disease 2019 (COVIDâ€19) outbreak is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARSâ€CoVâ€2) with considerable mortality worldwide. The main clinical manifestation of COVIDâ€19 is the presence of respiratory symptoms, but some patients develop severe cardiovascular and renal complications. There is an urgency to understand the mechanism by which this virus causes complications so as to develop treatment options. Curcumin, a natural polyphenolic compound, could be a potential treatment option for patients with coronavirus disease. In this study, we review some of the potential effects of curcumin such as inhibiting the entry of virus to the cell, inhibiting encapsulation of the virus and viral protease as well as modulating various cellular signaling pathways. This review provides a basis for further research and development of clinical applications of curcumin for the treatment of newly emerged SARSâ€CoVâ€2. This article is protected by copyright. All rights reserved.
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