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Author: Eftekhari, Aziz; Alipour, Mahdieh; Chodari, Leila; Maleki Dizaj, Solmaz; Ardalan, Mohammadreza; Samiei, Mohammad; Sharifi, Simin; Zununi Vahed, Sepideh; Huseynova, Irada; Khalilov, Rovshan; Ahmadian, Elham; Cucchiarini, Magali
Title: A Comprehensive Review of Detection Methods for SARS-CoV-2
  • Cord-id: ql1m2j32
  • Document date: 2021_1_22
    • ID: ql1m2j32
    Snippet: Recently, the outbreak of the coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, in China and its subsequent spread across the world has caused numerous infections and deaths and disrupted normal social activity. Presently, various techniques are used for the diagnosis of SARS-CoV-2 infection, with various advantages and weaknesses to each. In this paper, we summarize promising methods, such as reverse transcription-polymerase chain reaction (RT-PCR), serological testing, point
    Document: Recently, the outbreak of the coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, in China and its subsequent spread across the world has caused numerous infections and deaths and disrupted normal social activity. Presently, various techniques are used for the diagnosis of SARS-CoV-2 infection, with various advantages and weaknesses to each. In this paper, we summarize promising methods, such as reverse transcription-polymerase chain reaction (RT-PCR), serological testing, point-of-care testing, smartphone surveillance of infectious diseases, nanotechnology-based approaches, biosensors, amplicon-based metagenomic sequencing, smartphone, and wastewater-based epidemiology (WBE) that can also be utilized for the detection of SARS-CoV-2. In addition, we discuss principles, advantages, and disadvantages of these detection methods, and highlight the potential methods for the development of additional techniques and products for early and fast detection of SARS-CoV-2.

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