Author: Chang Ha Woo; Sungho Jang; Giyoung Shin; Gyoo Yeol Jung; Jeong Wook Lee
Title: Sensitive one-step isothermal detection of pathogen-derived RNAs Document date: 2020_3_9
ID: 1uqjmeic_37
Snippet: In addition to the results shown in this study, we expect that SENSR has a broad range 316 of possibilities for pathogen detection. First, SENSR can be easily implemented in the initial 317 screening of infectious diseases at places where a large number of people gather and 318 transfer 35,36 . With a short turnaround time and a simple reaction composition, SENSR is an 319 ideal diagnostic test for rapid and economical screening. Second, SENSR wi.....
Document: In addition to the results shown in this study, we expect that SENSR has a broad range 316 of possibilities for pathogen detection. First, SENSR can be easily implemented in the initial 317 screening of infectious diseases at places where a large number of people gather and 318 transfer 35,36 . With a short turnaround time and a simple reaction composition, SENSR is an 319 ideal diagnostic test for rapid and economical screening. Second, SENSR will be a valuable 320 platform for the immediate development of diagnostic tests for emerging pathogens 1,37 321 because of the simple probe design process and broad adaptability of SENSR. In this work, 322 we demonstrated the successful application of SENSR to six pathogens, using minimal 323 redesign based on the highly modular structure of the probes. In theory, SENSR detection 324 probes can be designed for any RNA as long as the target nucleic acid sequence is available. 325
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