Author: Regan, James; Flynn, James P; Rosenthal, Alexandra; Jordan, Hannah; Li, Yijia; Chishti, Rida; Giguel, Francoise; Corry, Heather; Coxen, Kendyll; Fajnzylber, Jesse; Gillespie, Elizabeth; Kuritzkes, Daniel R; Hacohen, Nir; Goldberg, Marcia B; Filbin, Michael R; Yu, Xu G; Baden, Lindsey; Ribeiro, Ruy M; Perelson, Alan S; Conway, Jessica M; Li, Jonathan Z
Title: Viral Load Kinetics of SARS-CoV-2 In Hospitalized Individuals with COVID-19 Cord-id: y4cbatxe Document date: 2021_4_17
ID: y4cbatxe
Snippet: SARS-CoV-2 kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms while peak viremia occurred within a week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. Remdesivir treatment was associated with faster rates of viral decay.
Document: SARS-CoV-2 kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms while peak viremia occurred within a week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. Remdesivir treatment was associated with faster rates of viral decay.
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