Selected article for: "RNA virus and viral binding"
Author: Yafei Wang; Randy Heiland; Morgan Craig; Courtney L. Davis; Ashlee N Ford Versypt; Adrianne Jenner; Jonathan Ozik; Nicholson Collier; Chase Cockrell; Andrew Becker; Gary An; James A. Glazier; Aarthi Narayanan; Amber M Smith; Paul Macklin
Title: Rapid community-driven development of a SARS-CoV-2 tissue simulator
  • Document date: 2020_4_5
    • ID: lq4tcyh4_80
    Snippet: Some have modeled intracellular virus replication, including very detailed models used for understanding replication and intervention points 43, 73 , typically using systems of ODEs 74, 75 . These models often include virus-receptor binding, receptor trafficking, endocytosis, viral uncoating, RNA transcription, protein synthesis, viral assembly, and viral exocytosis. However, to date no such model has been integrated with detailed spatiotemporal .....
    Document: Some have modeled intracellular virus replication, including very detailed models used for understanding replication and intervention points 43, 73 , typically using systems of ODEs 74, 75 . These models often include virus-receptor binding, receptor trafficking, endocytosis, viral uncoating, RNA transcription, protein synthesis, viral assembly, and viral exocytosis. However, to date no such model has been integrated with detailed spatiotemporal models of viral propagation in 3-D tissues with dynamical models of immune interactions.

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