Author: Qizhi Sun; Mohamed I. Gatie; Gregory M. Kelly
Title: Serum-dependent and independent regulation of PARP2 Document date: 2018_11_29
ID: ccfrx3md_30
Snippet: However, in the case of a cell stress response when serum is removed, PARP2, through an 547 unknown mechanism, is no longer in a SDS or urea soluble form, and it is not known if 548 this is a prelude to apoptosis or to some other physiological requirement. Nevertheless, 549 alleviating this cellular stress by the addition of serum recycles PARP2 to a form, thereby 550 allowing it to resume its enzymatic role involved in the pARylation of target s.....
Document: However, in the case of a cell stress response when serum is removed, PARP2, through an 547 unknown mechanism, is no longer in a SDS or urea soluble form, and it is not known if 548 this is a prelude to apoptosis or to some other physiological requirement. Nevertheless, 549 alleviating this cellular stress by the addition of serum recycles PARP2 to a form, thereby 550 allowing it to resume its enzymatic role involved in the pARylation of target substrates. 551 All rights reserved. No reuse allowed without permission.
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