Selected article for: "alpha cov and beta cov"

Author: NISREEN M.A. OKBA; Marcel A Muller; Wentao Li; Chunyan Wang; Corine H. GeurtsvanKessel; Victor M. Corman; Mart M. Lamers; Reina S. Sikkema; Erwin de Bruin; Felicity D. Chandler; Yazdan Yazdanpanah; Quentin Le Hingrat; Diane Descamps; Nadhira Houhou-Fidouh; Chantal B. E. M. Reusken; Berend-Jan Bosch; Christian Drosten; Marion P.G. Koopmans; Bart L. Haagmans
Title: SARS-CoV-2 specific antibody responses in COVID-19 patients
  • Document date: 2020_3_20
  • ID: 9595vm0k_31
    Snippet: We further assessed the specificity of the S1 assay using cohorts A-E (Table 1) comprising of sera from healthy blood donors (A), PCR-confirmed acute respiratory non-CoV infections (B), acute to convalescent PCR-confirmed alpha-and beta-HCoV infections (C), and PCR-confirmed MERS-CoV (D) and SARS-CoV (E) infections. None of the sera from specificity cohorts A-D were reactive in our in-house S1 ELISA at the set cut-off indicating 100% specificity,.....
    Document: We further assessed the specificity of the S1 assay using cohorts A-E (Table 1) comprising of sera from healthy blood donors (A), PCR-confirmed acute respiratory non-CoV infections (B), acute to convalescent PCR-confirmed alpha-and beta-HCoV infections (C), and PCR-confirmed MERS-CoV (D) and SARS-CoV (E) infections. None of the sera from specificity cohorts A-D were reactive in our in-house S1 ELISA at the set cut-off indicating 100% specificity, whereas sera from SARS-CoV patients cross-reacted (Figure 2A) .

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