Selected article for: "alternative approach and distress syndrome"

Author: Laura E Lamb; Sarah N Bartolone; Elijah Ward; Michael B Chancellor
Title: Rapid Detection of Novel Coronavirus (COVID-19) by Reverse Transcription-Loop-Mediated Isothermal Amplification
  • Document date: 2020_2_24
  • ID: 6kpgt70s_20
    Snippet: Given the rapid emergence of COVID-19 and the severe complications that can result including acute respiratory distress syndrome (ARDS) and pneumonia, improved diagnostic options that are fast, reliable, easy, and affordable are required. This is critical since COVID-19 infection can rapidly progress from hospital admission to ARDS in as few as 2 days, and COVID-19 infection can be fatal. 1 Conventional qRT-PCR, while specific and sensitive, must.....
    Document: Given the rapid emergence of COVID-19 and the severe complications that can result including acute respiratory distress syndrome (ARDS) and pneumonia, improved diagnostic options that are fast, reliable, easy, and affordable are required. This is critical since COVID-19 infection can rapidly progress from hospital admission to ARDS in as few as 2 days, and COVID-19 infection can be fatal. 1 Conventional qRT-PCR, while specific and sensitive, must be done by trained personnel on specialized equipment at a qualified laboratory. Since this disease is spreading rapidly, centralized labs may have trouble keeping up with testing demands or may need an alternative approach if qRT-PCR kits are not available. This feasibility study demonstrated that RT-LAMP allows rapid detection of COVID-19 in a variety of All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.

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