A Simple Ventilator Designed To Be Used in Shortage Crises: Construction and Verification Testing

Akerib, Daniel S; Ames, Andrew; Breidenbach, Martin; Bressack, Michael; Breur, Pieter A; Charles, Eric; Gaba, David M; Herbst, Ryan; Ignarra, Christina M; Luitz, Steffen; Miller, Eric H; Mong, Brian; Shutt, Tom A; Wittgen, Matthias

BACKGROUND: The COVID-19 pandemic has demonstrated the possibility of severe ventilator shortages in the near future. OBJECTIVE: We aimed to develop an acute shortage ventilator. METHODS: The ventilator was designed to mechanically compress a self-inflating bag resuscitator, using a modified ventilator patient circuit, which is controlled by a microcontroller and an optional laptop. It was designed to operate in both volume-controlled mode and pressure-controlled assist modes. We tested the ventilator in 4 modes using an artificial lung while measuring the volume, flow, and pressure delivered over time by the ventilator. RESULTS: The ventilator was successful in reaching the desired tidal volume and respiratory rates specified in national emergency use resuscitator system guidelines. The ventilator responded to simulated spontaneous breathing. CONCLUSIONS: The key design goals were achieved. We developed a simple device with high performance for short-term use, made primarily from common hospital parts and generally available nonmedical components to avoid any compatibility or safety issues with the patient, and at low cost, with a unit cost per ventilator is less than $400 US excluding the patient circuit parts, that can be easily manufactured.