Selected article for: "PEDv porcine epidemic diarrhea virus and porcine epidemic diarrhea virus"
Author: Lucia Grenga; Fabrice Gallais; Olivier Pible; Jean-Charles Gaillard; Duarte Gouveia; Hélène Batina; Niza Bazaline; Sylvie Ruat; Karen Culotta; Guylaine Miotello; Stéphanie Debroas; Marie-Anne Roncato; Gérard Steinmetz; Charlotte Foissard; Anne Desplan; Béatrice Alpha-Bazin; Christine Almunia; Fabienne Gas; Laurent Bellanger; Jean Armengaud
Title: Shotgun proteomics of SARS-CoV-2 infected cells and its application to the optimisation of whole viral particle antigen production for vaccines
  • Document date: 2020_4_17
    • ID: kd02dehk_4
    Snippet: Multiple proteomics strategies have been shown insightful for better understanding of coronavirus structure and its molecular mechanisms of infection. Tracheal tissues of chicken infected with infectious bronchitis coronavirus were analyzed by 2D-DIGE and MALDI-TOF tandem mass spectrometry to establish the host response [7] . Vero cells infected with porcine epidemic diarrhea virus (PEDV) were analyzed by shotgun proteomics [8] . Different PEDV c.....
    Document: Multiple proteomics strategies have been shown insightful for better understanding of coronavirus structure and its molecular mechanisms of infection. Tracheal tissues of chicken infected with infectious bronchitis coronavirus were analyzed by 2D-DIGE and MALDI-TOF tandem mass spectrometry to establish the host response [7] . Vero cells infected with porcine epidemic diarrhea virus (PEDV) were analyzed by shotgun proteomics [8] . Different PEDV coronavirus strains were compared with an iTRAQ-labeling quantitative approach showing differences of inflammatory cascade eliciting [9] . The dynamics of the host proteins triggered by specific overexpressed coronavirus genes was also established [10] . While no literature is yet available on the proteomics characterization of author/funder. All rights reserved. No reuse allowed without permission.

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