Author: de la Cruz-Benito, Beatriz; Rivas-Pollmar, MarÃa I; Ãlvarez Román, MarÃa T; Trelles-MartÃnez, Roberto; MartÃn-Salces, Monica; Lázaro-Del Campo, Paula; RamÃrez-López, Andrés; GarcÃa-Barcenilla, Sara; Cebanu, Tamara; Acuña-Butta, Paula; Monzón-Manzano, Elena; González-Zorrilla, Elena; Jiménez-Yuste, Victor; Butta, Nora V
Title: Paradoxical effect of SARS-CoV-2 infection in patients with immune thrombocytopenia. Cord-id: vez0pzi7 Document date: 2020_9_10
ID: vez0pzi7
Snippet: Thrombocytopenia has been identified as a common complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the general population. In an attempt to determine the impact of coronavirus disease 2019 (COVID-19) in patients with immune thrombocytopenia (ITP), a retrospective single-centre study was performed. Thrombocytosis was observed in patients with chronic ITP after SARS-CoV-2 infection, frequently needing treatment adjustment or even discontinuation of therapy.
Document: Thrombocytopenia has been identified as a common complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the general population. In an attempt to determine the impact of coronavirus disease 2019 (COVID-19) in patients with immune thrombocytopenia (ITP), a retrospective single-centre study was performed. Thrombocytosis was observed in patients with chronic ITP after SARS-CoV-2 infection, frequently needing treatment adjustment or even discontinuation of therapy. Relapses and newly diagnosed cases showed a fast response after initial treatment compared to ITP. Reduced immune activity due to lymphopenia during COVID-19 could explain this paradoxical effect, although further studies are needed.
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