Acute Myocardial Injury of Patients with Coronavirus Disease 2019

Huayan Xu; Keke Hou; Hong Xu; Zhenlin Li; Huizhu Chen; Na Zhang; Rong Xu; Hang Fu; Ran Sun; Lingyi Wen; Linjun Xie; Hui Liu; Kun Zhang; Joseph B Selvanayagam; Chuan Fu; Shihua Zhao; Zhigang Yang; Ming Yang; Yingkun Guo

The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.05.20031591 doi: medRxiv preprint approximately 25.2% of the patients had at least one underlying disorder, such as hypertension and COPD, and an underlying disorder potentially acts as an important risk factor for poor outcomes. 25 We found that the severity of NCP was closely correlated with the AMI occurrence. Meanwhile, ARDS was present in all the AMI patients. ARDS, as a severe complication, occurred in approximately 19%-29% NCP patients as per previous reports. [2] [3] [4] [5] Thus, we must understand the mechanisms of heart-lung interactions in ARDS patients, particularly the right ventricle function impairments caused by respiratory dysfunction. 26 Logistic regression analysis indicated that NCP severity was a risk factor for AMI in COVID-19 patients. Indeed, the outcomes of these patients need to be further determined in long-term follow-up studies.