Author: Chang Ha Woo; Sungho Jang; Giyoung Shin; Gyoo Yeol Jung; Jeong Wook Lee
Title: Sensitive one-step isothermal detection of pathogen-derived RNAs Document date: 2020_3_9
ID: 1uqjmeic_7
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03.05.20031971 doi: medRxiv preprint 5 transcription events from the full-length, ligated probe by T7 RNA polymerase and 2) the 104 presence of target RNA sequence on the full-length transcript which could be utilized as an 105 additional splint for unligated probes in the reaction mixture. Accordingly, SENSR could 106 enable sensitive RNA detec.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03.05.20031971 doi: medRxiv preprint 5 transcription events from the full-length, ligated probe by T7 RNA polymerase and 2) the 104 presence of target RNA sequence on the full-length transcript which could be utilized as an 105 additional splint for unligated probes in the reaction mixture. Accordingly, SENSR could 106 enable sensitive RNA detection without any pre-amplification steps. 107 108
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