Author: Eric Anthony Coomes; Hourmazd Haghbayan
Title: Interleukin-6 in COVID-19: A Systematic Review and Meta-Analysis Document date: 2020_4_3
ID: nadcsiii_36
Snippet: It is increasingly recognized that a dysregulated host immune response to foreign infectious pathogens is integral to the development of target organ dysfunction and a major contributor to morbidity and mortality. Specifically, the systemic inflammatory response in sepsis has been demonstrated to overlap with that of CRS;44,45 in patients with COVID-19 complicated by ARDS, such a hyperactivation of the humoral immune system with a prominent IL-6 .....
Document: It is increasingly recognized that a dysregulated host immune response to foreign infectious pathogens is integral to the development of target organ dysfunction and a major contributor to morbidity and mortality. Specifically, the systemic inflammatory response in sepsis has been demonstrated to overlap with that of CRS;44,45 in patients with COVID-19 complicated by ARDS, such a hyperactivation of the humoral immune system with a prominent IL-6 response may suggest that part of the pathogenesis of complicated disease involves a . CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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