Selected article for: "brush border and digestive system"
Author: Ashutosh Kumar; Muneeb A. Faiq; Vikas Pareek; Khursheed Raza; Ravi K. Narayan; Pranav Prasoon; Pavan Kumar; Maheswari Kulandhasamy; Chiman Kumari; Kamla Kant; Himanshu N. Singh; Rizwana Qadri; Sada N. Pandey; Santosh Kumar
Title: Relevance of enriched expression of SARS-CoV-2 binding receptor ACE2 in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients
  • Document date: 2020_4_15
    • ID: gpzyiuo7_5
    Snippet: The correlated expression (genomic and proteomic) of ACE2 (to which SARS-CoV-2 binds through the S-spike) was found to be enriched in the lower gastrointestinal tract (GIT) (highest in small intestine, followed by colon and rectum), and was undetectable in the upper GIT components: mouth cavity (tongue, oral mucosa, and salivary glands), esophagus, and stomach. High expression of ACE2 was noted in the glandular cells as well as in the enterocytes.....
    Document: The correlated expression (genomic and proteomic) of ACE2 (to which SARS-CoV-2 binds through the S-spike) was found to be enriched in the lower gastrointestinal tract (GIT) (highest in small intestine, followed by colon and rectum), and was undetectable in the upper GIT components: mouth cavity (tongue, oral mucosa, and salivary glands), esophagus, and stomach. High expression of ACE2 was noted in the glandular cells as well as in the enterocytes in the lining epithelium (including brush border epithelium). Among other digestive system organs, gallbladder (GB) showed high expression of ACE2 in glandular cells, while any protein expression was undetectable in liver and pancreas.

    Search related documents:
    Co phrase search for related documents
    • brush border and gastrointestinal tract: 1, 2, 3, 4, 5, 6
    • brush border and high expression: 1, 2, 3, 4, 5, 6, 7
    • brush border and mouth cavity: 1, 2, 3
    • brush border and oral mucosa: 1, 2, 3
    • brush border and pancreas liver: 1, 2
    • brush border and protein expression: 1, 2, 3, 4, 5, 6, 7, 8
    • brush border and rectum colon: 1, 2, 3
    • brush border epithelium and correlated expression: 1
    • brush border epithelium and gastrointestinal tract: 1
    • brush border epithelium and high expression: 1, 2
    • brush border epithelium and mouth cavity: 1, 2, 3
    • brush border epithelium and oral mucosa: 1, 2, 3
    • brush border epithelium and pancreas liver: 1, 2
    • brush border epithelium and protein expression: 1, 2, 3
    • brush border epithelium and rectum colon: 1, 2, 3
    • correlated expression and gastrointestinal tract: 1, 2, 3, 4, 5, 6, 7
    • correlated expression and glandular cell: 1
    • correlated expression and high expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • correlated expression and mouth cavity: 1