Author: Naoto Hori; Natalia A. Denesyuk; D. Thirumalai
Title: Salt Effects on the Thermodynamics of a Frameshifting RNA Pseudoknot under Tension Document date: 2016_4_15
ID: 08mep8hm_14
Snippet: In order to obtain the phase diagram in the [C, f ] plane of the BWYV PK, we performed a series of low friction Langevin dynamics simulations by varying the salt concentration from 5 to 1200 mM and the mechanical force from 0 to 20 pN, at a constant temperature of 50 • C. We varied C by changing the Debye length in the simulations, and the mechanical force was externally applied to the terminal nucleotides ( Fig. 1A) ......
Document: In order to obtain the phase diagram in the [C, f ] plane of the BWYV PK, we performed a series of low friction Langevin dynamics simulations by varying the salt concentration from 5 to 1200 mM and the mechanical force from 0 to 20 pN, at a constant temperature of 50 • C. We varied C by changing the Debye length in the simulations, and the mechanical force was externally applied to the terminal nucleotides ( Fig. 1A) .
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