Author: Patrick Hunziker; Urs Zenklusen
Title: Ad-hoc Assembly of Lean Extracorporeal Membrane Oxygenation Systems for COVID-19 Document date: 2020_4_17
ID: 41v5shpt_8
Snippet: Using the Impella CP, blood flows of up to 3.6L/min of saline (minimal circuit) and of 3.5L/min of blood (complete system) could be achieved at pump performance level 9: pressure gradients and flows across the system remained stable over 48 hours. Flows were at least as high as predicted by combining pump performance and component pressure drop charts. The combination of pump performance chart, cannula pressure drop chart and experimental observa.....
Document: Using the Impella CP, blood flows of up to 3.6L/min of saline (minimal circuit) and of 3.5L/min of blood (complete system) could be achieved at pump performance level 9: pressure gradients and flows across the system remained stable over 48 hours. Flows were at least as high as predicted by combining pump performance and component pressure drop charts. The combination of pump performance chart, cannula pressure drop chart and experimental observations indicates that when using large enough cannuals, the "sweet spot" for Impella CP based systems is between 2.8 and 3.5 L/min, while for Impella 5.0, it is between 3.5 and 4.5 L/min.
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