Selected article for: "RNA sequence and sequence information"

Author: Taiaroa, George; Rawlinson, Daniel; Featherstone, Leo; Pitt, Miranda; Caly, Leon; Druce, Julian; Purcell, Damian; Harty, Leigh; Tran, Thomas; Roberts, Jason; Scott, Nichollas; Catton, Mike; Williamson, Deborah; Coin, Lachlan; Duchene, Sebastian
Title: Direct RNA sequencing and early evolution of SARS-CoV-2
  • Cord-id: x3hr1y6o
  • Document date: 2020_4_3
  • ID: x3hr1y6o
    Snippet: Fundamental aspects of SARS-CoV-2 biology remain to be described, having the potential to provide insight to the response effort for this high-priority pathogen. Here we describe the first native RNA sequence of SARS-CoV-2, detailing the coronaviral transcriptome and epitranscriptome, and share these data publicly. A data-driven inference of viral genetic features and evolutionary rate is also made. The rapid sharing of sequence information throughout the SARS-CoV-2 pandemic represents an inflec
    Document: Fundamental aspects of SARS-CoV-2 biology remain to be described, having the potential to provide insight to the response effort for this high-priority pathogen. Here we describe the first native RNA sequence of SARS-CoV-2, detailing the coronaviral transcriptome and epitranscriptome, and share these data publicly. A data-driven inference of viral genetic features and evolutionary rate is also made. The rapid sharing of sequence information throughout the SARS-CoV-2 pandemic represents an inflection point for public health and genomic epidemiology, providing early insights into the biology and evolution of this emerging pathogen.

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