Author: Chunyun Sun; Long Chen; Ji Yang; Chunxia Luo; Yanjing Zhang; Jing Li; Jiahui Yang; Jie Zhang; Liangzhi Xie
Title: SARS-CoV-2 and SARS-CoV Spike-RBD Structure and Receptor Binding Comparison and Potential Implications on Neutralizing Antibody and Vaccine Development Document date: 2020_2_20
ID: nhq0oq8y_5
Snippet: with ACE2 by computational modeling and binding free energy analysis. We also used the recombinant S1 proteins of the two viruses to compare their binding curves to both recombinant ACE2 protein and ACE2 expressing cells. The above studies confirm that both SARS-CoV-2 and SARS-CoV have similar binding affinities to the human receptor ACE2......
Document: with ACE2 by computational modeling and binding free energy analysis. We also used the recombinant S1 proteins of the two viruses to compare their binding curves to both recombinant ACE2 protein and ACE2 expressing cells. The above studies confirm that both SARS-CoV-2 and SARS-CoV have similar binding affinities to the human receptor ACE2.
Search related documents:
Co phrase search for related documents- bind affinity and free energy analysis: 1
- bind affinity and human receptor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- bind affinity and S1 protein: 1
- computational modeling and energy analysis: 1, 2
- computational modeling and free energy analysis: 1, 2
- computational modeling and human receptor: 1, 2, 3, 4, 5, 6
- computational modeling and S1 protein: 1
- energy analysis and free energy analysis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- energy analysis and human receptor: 1, 2, 3, 4
- energy analysis and S1 protein: 1
- express cell and human receptor: 1, 2, 3, 4
- express cell and S1 protein: 1, 2, 3
- free energy analysis and human receptor: 1, 2, 3
- free energy analysis and S1 protein: 1
- human receptor and S1 protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- human receptor and virus S1 protein: 1, 2, 3, 4, 5
- recombinant virus S1 protein and S1 protein: 1, 2, 3
- recombinant virus S1 protein and virus S1 protein: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date