Author: Lucia Grenga; Fabrice Gallais; Olivier Pible; Jean-Charles Gaillard; Duarte Gouveia; Hélène Batina; Niza Bazaline; Sylvie Ruat; Karen Culotta; Guylaine Miotello; Stéphanie Debroas; Marie-Anne Roncato; Gérard Steinmetz; Charlotte Foissard; Anne Desplan; Béatrice Alpha-Bazin; Christine Almunia; Fabienne Gas; Laurent Bellanger; Jean Armengaud
Title: Shotgun proteomics of SARS-CoV-2 infected cells and its application to the optimisation of whole viral particle antigen production for vaccines Document date: 2020_4_17
ID: kd02dehk_29
Snippet: Concomitantly with vaccine development, inactivated virus particles are also of interest for testing real serology or screening neutralizing antibodies. Evidently, production of well-characterized active virus particles is also of interest for fundamental research purposes. Given the requirement for speed, here we evaluate the use of LC-MS/MS as a tool for guiding the optimisation of the conditions for SARS-CoV-2 whole viral particle antigen prod.....
Document: Concomitantly with vaccine development, inactivated virus particles are also of interest for testing real serology or screening neutralizing antibodies. Evidently, production of well-characterized active virus particles is also of interest for fundamental research purposes. Given the requirement for speed, here we evaluate the use of LC-MS/MS as a tool for guiding the optimisation of the conditions for SARS-CoV-2 whole viral particle antigen production.
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