Author: Kusadasi, Nuray; Sikma, Maaike; Huisman, Albert; Westerink, Jan; Maas, Coen; Schutgens, Roger
Title: A Pathophysiological Perspective on the SARS-CoV-2 Coagulopathy Cord-id: yu2i0u2h Document date: 2020_8_10
ID: yu2i0u2h
Snippet: Recent evidence is focusing on the presence of a hypercoagulable state with development of both venous and arterial thromboembolic complications in patients infected with SARS-CoV-2. The ongoing activation of coagulation related to the severity of the illness is further characterized by thrombotic microangiopathy and endotheliitis. These microangiopathic changes cannot be classified as classical disseminated intravascular coagulation (DIC). In this short review we describe the interaction betwee
Document: Recent evidence is focusing on the presence of a hypercoagulable state with development of both venous and arterial thromboembolic complications in patients infected with SARS-CoV-2. The ongoing activation of coagulation related to the severity of the illness is further characterized by thrombotic microangiopathy and endotheliitis. These microangiopathic changes cannot be classified as classical disseminated intravascular coagulation (DIC). In this short review we describe the interaction between coagulation and inflammation with focus on the possible mechanisms that might be involved in SARS-CoV-2 infection associated coagulopathy in the critically ill.
Search related documents:
Co phrase search for related documents- activatable fibrinolysis inhibitor and lung injury: 1
- additional function and lung injury: 1
Co phrase search for related documents, hyperlinks ordered by date