Author: Jean-Louis, Girardin; Turner, Arlener D; Jin, Peng; Liu, Mengling; Boutin-Foster, Carla; McFarlane, Samy I; Seixas, Azizi
Title: Increased Metabolic Burden Among Blacks: A Putative Mechanism for Disparate COVID-19 Outcomes Cord-id: y58nvjqd Document date: 2020_10_2
ID: y58nvjqd
Snippet: Mounting evidence shows a disproportionate COVID-19 burden among Blacks. Early findings indicate pre-existing metabolic burden (eg, obesity, hypertension and diabetes) as key drivers of COVID-19 severity. Since Blacks exhibit higher prevalence of metabolic burden, we examined the influence of metabolic syndrome on disparate COVID-19 burden. We analyzed data from a NIH-funded study to characterize metabolic burden among Blacks in New York (Metabolic Syndrome Outcome Study). Patients (n=1035) were
Document: Mounting evidence shows a disproportionate COVID-19 burden among Blacks. Early findings indicate pre-existing metabolic burden (eg, obesity, hypertension and diabetes) as key drivers of COVID-19 severity. Since Blacks exhibit higher prevalence of metabolic burden, we examined the influence of metabolic syndrome on disparate COVID-19 burden. We analyzed data from a NIH-funded study to characterize metabolic burden among Blacks in New York (Metabolic Syndrome Outcome Study). Patients (n=1035) were recruited from outpatient clinics, where clinical and self-report data were obtained. The vast majority of the sample was overweight/obese (90%); diagnosed with hypertension (93%); dyslipidemia (72%); diabetes (61%); and nearly half of them were at risk for sleep apnea (48%). Older Blacks (age≥65 years) were characterized by higher levels of metabolic burden and co-morbidities (eg, heart disease, cancer). In multivariate-adjusted regression analyses, age was a significant (p≤.001) independent predictor of hypertension (OR=1.06; 95% CI: 1.04–1.09), diabetes (OR=1.03; 95% CI: 1.02–1.04), and dyslipidemia (OR=0.98; 95% CI: 0.97–0.99), but not obesity. Our study demonstrates an overwhelmingly high prevalence of the metabolic risk factors related to COVID-19 among Blacks in New York, highlighting disparate metabolic burden among Blacks as a possible mechanism conferring the greater burden of COVID-19 infection and mortality represented in published data.
Search related documents:
Co phrase search for related documents- logistic regression and lonely feel: 1
- logistic regression and long duration sleep: 1, 2
- logistic regression and long significant: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- logistic regression and low annual income: 1
- logistic regression and low density: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27
- logistic regression and low density lipoprotein cholesterol: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- logistic regression and low density lipoprotein cholesterol ldl: 1, 2, 3, 4, 5, 6, 7, 8
- logistic regression and low level depression: 1, 2
- logistic regression and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- logistic regression model and long significant: 1, 2, 3
- logistic regression model and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- long significant and low density: 1
- long significant and lung disease: 1, 2
- low density and lung disease: 1, 2, 3, 4, 5, 6
- low density lipoprotein cholesterol and lung disease: 1
Co phrase search for related documents, hyperlinks ordered by date