Author: Williams, Anna Marie; Liang, Mingyu
Title: Small RNAs pack a punch in human kidney disease. Cord-id: yalu66t9 Document date: 2020_8_1
ID: yalu66t9
Snippet: microRNAs play prominent regulatory roles by inducing target mRNA degradation or translational repression. Several studies have highlighted the power of microRNAs as biomarkers and potential mechanistic mediators of human kidney disease. Small RNA deep sequencing libraries can be generated from minute amounts of formalin-fixed paraffin-embedded tissues including specific tissue regions. Such analyses have unique advantages and may complement analyses of fresh kidney specimens to advance tissue f
Document: microRNAs play prominent regulatory roles by inducing target mRNA degradation or translational repression. Several studies have highlighted the power of microRNAs as biomarkers and potential mechanistic mediators of human kidney disease. Small RNA deep sequencing libraries can be generated from minute amounts of formalin-fixed paraffin-embedded tissues including specific tissue regions. Such analyses have unique advantages and may complement analyses of fresh kidney specimens to advance tissue functional genomics-based precision medicine for human kidney disease.
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