Author: Labro, Guylaine; Jandeaux, Louise Marie; Rusu, Andreea; Virot, Edouard; Pointurier, Valentin; Pinto, Luis; Mathien, Cyrille; Debliquis, Agathe; Harzallah, Ines; Mootien, Joy; Drenou, Bernard; Kuteifan, Khaldoun
Title: Macrophage Activation in COVID-19 Patients in Intensive Care Unit Cord-id: uelam5ix Document date: 2020_6_29
ID: uelam5ix
Snippet: We report six cases of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, admitted to intensive care unit (ICU), for whom bone marrow aspirate revealed hemophagocytosis. We compared their clinical presentation and laboratory findings to those that can be encountered during a hemophagocytic lymphohistiocytosis. These observations might evoke a macrophage activation mechanism different from the one encountered in the hemophagocytic lymphohistiocytosis (HLH).
Document: We report six cases of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, admitted to intensive care unit (ICU), for whom bone marrow aspirate revealed hemophagocytosis. We compared their clinical presentation and laboratory findings to those that can be encountered during a hemophagocytic lymphohistiocytosis. These observations might evoke a macrophage activation mechanism different from the one encountered in the hemophagocytic lymphohistiocytosis (HLH).
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