Author: Neha Jain; Uma Shankar; Prativa Majee; Amit Kumar
Title: Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes Document date: 2020_4_1
ID: lmstdmyb_1
Snippet: should robustly activate both the humoral and the cell-mediated immunity to establish strong protection against the pathogen [10] . The antibody generation by B-cell activation as well as acute viral clearance by T-cells along with virus-specific memory generation by CD8+ Tcells are equally important to develop immunity against the coronavirus [11] . In case of respiratory virus like coronaviruses, the mucosal immunity plays an essential role and.....
Document: should robustly activate both the humoral and the cell-mediated immunity to establish strong protection against the pathogen [10] . The antibody generation by B-cell activation as well as acute viral clearance by T-cells along with virus-specific memory generation by CD8+ Tcells are equally important to develop immunity against the coronavirus [11] . In case of respiratory virus like coronaviruses, the mucosal immunity plays an essential role and therefore route of administration of the vaccine is also important in the context of vaccine development. Vaccines designed against previously reported SARS-CoV and MERS-CoV majorly focuses on the Spike protein of virus which consists of S1 and S2 subunits bearing the receptor binding domain (RBD) of the virus and cell fusion machinery respectively.
Search related documents:
Co phrase search for related documents- antibody generation and coronavirus immunity: 1
- antibody generation and essential role: 1, 2
- antibody generation and essential role play: 1
- antibody generation and memory generation: 1, 2, 3, 4, 5
- antibody generation and Spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
- antibody generation and vaccine administration: 1
- antibody generation and vaccine development: 1, 2, 3, 4, 5
- antibody generation and viral clearance: 1
- antibody generation and virus Spike protein: 1, 2, 3
- bind domain and cell fusion: 1, 2, 3, 4
- bind domain and cell mediate: 1
- bind domain and essential role: 1
- bind domain and mucosal immunity: 1
- bind domain and RBD receptor bind domain: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51
- bind domain and receptor bind domain: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- bind domain and respiratory virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- bind domain and Spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60
- bind domain and vaccine development: 1, 2, 3, 4, 5, 6
- bind domain and virus Spike protein: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date