Author: Neha Jain; Uma Shankar; Prativa Majee; Amit Kumar
Title: Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes Document date: 2020_4_1
ID: lmstdmyb_1
Snippet: should robustly activate both the humoral and the cell-mediated immunity to establish strong protection against the pathogen [10] . The antibody generation by B-cell activation as well as acute viral clearance by T-cells along with virus-specific memory generation by CD8+ Tcells are equally important to develop immunity against the coronavirus [11] . In case of respiratory virus like coronaviruses, the mucosal immunity plays an essential role and.....
Document: should robustly activate both the humoral and the cell-mediated immunity to establish strong protection against the pathogen [10] . The antibody generation by B-cell activation as well as acute viral clearance by T-cells along with virus-specific memory generation by CD8+ Tcells are equally important to develop immunity against the coronavirus [11] . In case of respiratory virus like coronaviruses, the mucosal immunity plays an essential role and therefore route of administration of the vaccine is also important in the context of vaccine development. Vaccines designed against previously reported SARS-CoV and MERS-CoV majorly focuses on the Spike protein of virus which consists of S1 and S2 subunits bearing the receptor binding domain (RBD) of the virus and cell fusion machinery respectively.
Search related documents:
Co phrase search for related documents- antibody generation and coronavirus immunity: 1
- antibody generation and essential role: 1, 2
- antibody generation and essential role play: 1
- antibody generation and memory generation: 1, 2, 3, 4, 5
- bind domain and cell fusion: 1, 2, 3, 4
- bind domain and cell mediate: 1
- bind domain and essential role: 1
- bind domain and mucosal immunity: 1
- bind domain and RBD receptor bind domain: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell fusion and coronavirus immunity: 1
- cell fusion and essential role: 1, 2, 3, 4, 5, 6, 7
- cell fusion and essential role play: 1, 2
- cell fusion and mucosal immunity: 1, 2
- cell fusion and previously report: 1
- cell fusion virus and coronavirus immunity: 1
- cell fusion virus and essential role: 1, 2
- cell fusion virus and essential role play: 1
- coronavirus immunity and essential role: 1, 2
- coronavirus immunity and mucosal immunity: 1, 2, 3, 4, 5, 6
Co phrase search for related documents, hyperlinks ordered by date