Author: Neha Jain; Uma Shankar; Prativa Majee; Amit Kumar
Title: Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes Document date: 2020_4_1
ID: lmstdmyb_56
Snippet: An ideal vaccine should harbor conserved epitopes, have multi-valency and can elicit both cellular and humoral mediated immune response in the host. A subunit vaccine contains minimal elements that are antigenic and required for the stimulation of prolonged protective or therapeutic immune response. In the recent times, various reports have shown the construction of multi subunit vaccine by utilizing highly antigenic HTL, CTL and BCL epitopes. He.....
Document: An ideal vaccine should harbor conserved epitopes, have multi-valency and can elicit both cellular and humoral mediated immune response in the host. A subunit vaccine contains minimal elements that are antigenic and required for the stimulation of prolonged protective or therapeutic immune response. In the recent times, various reports have shown the construction of multi subunit vaccine by utilizing highly antigenic HTL, CTL and BCL epitopes. Herein, we constructed a multi-epitope vaccine candidate by combining 13 HTL, 12 CTL and 4 BCL epitopes that were highly conserved, antigenic, non-toxic and non-allergens ( Figure 4 ).
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