Author: Renhong Yan; Yuanyuan Zhang; Yingying Guo; Lu Xia; Qiang Zhou
Title: Structural basis for the recognition of the 2019-nCoV by human ACE2 Document date: 2020_2_20
ID: elo7kfun_4
Snippet: Structural elucidation of the interface between S protein-RBD and ACE2-PD will not only shed light on the mechanistic understanding of viral infection, but also facilitate development of viral detection techniques and potential antiviral therapeutics. Highresolution cryo-EM structural determination of the dimer of the ACE2-B 0 AT1 heterodimers established the framework for structural resolution of the ternary complex using single-particle cryo-EM.....
Document: Structural elucidation of the interface between S protein-RBD and ACE2-PD will not only shed light on the mechanistic understanding of viral infection, but also facilitate development of viral detection techniques and potential antiviral therapeutics. Highresolution cryo-EM structural determination of the dimer of the ACE2-B 0 AT1 heterodimers established the framework for structural resolution of the ternary complex using single-particle cryo-EM.
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