Author: Lyudmila Kovalchuke; Eugene V. Mosharov; Oren A. Levy; Lloyd A. Greene
Title: Stress-induced phospho-ubiquitin formation causes parkin degradation Document date: 2018_12_5
ID: ceepyyxj_28
Snippet: Significantly, it also abrogated L-DOPA-induced parkin loss, but by about half (L-DOPA: 61.1 ± 3.0% of untreated; L-DOPA + epoxomicin: 80.5 ± 3.3% of untreated, p = 0.001, N = 8), consistent with half of L-DOPA-induced parkin loss being phospho-Ub-dependent (Fig. 7B )......
Document: Significantly, it also abrogated L-DOPA-induced parkin loss, but by about half (L-DOPA: 61.1 ± 3.0% of untreated; L-DOPA + epoxomicin: 80.5 ± 3.3% of untreated, p = 0.001, N = 8), consistent with half of L-DOPA-induced parkin loss being phospho-Ub-dependent (Fig. 7B ).
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