Author: Shi, Pei-Yong; Xie, Xuping; Zou, Jing; Fontes-Garfias, Camila; Xia, Hongjie; Swanson, Kena; Cutler, Mark; Cooper, David; Menachery, Vineet; Weaver, Scott; Dormitzer, Philip
Title: Neutralization of N501Y mutant SARS-CoV-2 by BNT162b2 vaccine-elicited sera Cord-id: vm0nmls2 Document date: 2021_1_13
ID: vm0nmls2
Snippet: Rapidly spreading variants of SARS-CoV-2 that have arisen in the United Kingdom and South Africa share the spike N501Y substitution, which is of particular concern because it is located in the viral receptor binding site for cell entry and increases binding to the receptor. We generated isogenic N501 and Y501 SARS-CoV-2. Twenty human sera from the mRNA-based vaccine BNT162b2 trial exhibited equivalent neutralizing titers to the N501 and Y501 viruses.
Document: Rapidly spreading variants of SARS-CoV-2 that have arisen in the United Kingdom and South Africa share the spike N501Y substitution, which is of particular concern because it is located in the viral receptor binding site for cell entry and increases binding to the receptor. We generated isogenic N501 and Y501 SARS-CoV-2. Twenty human sera from the mRNA-based vaccine BNT162b2 trial exhibited equivalent neutralizing titers to the N501 and Y501 viruses.
Search related documents:
Co phrase search for related documents- Try single phrases listed below for: 1
Co phrase search for related documents, hyperlinks ordered by date