Author: Jennifer C.E Lane; James Weaver; Kristin Kostka; Talita Duarte-Salles; Maria Tereza F. Abrahao; Heba Alghoul; Osaid Alser; Thamir M Alshammari; Patricia Biedermann; Edward Burn; Paula Casajust; Mitch Conover; Aedin C. Culhane; Alexander Davydov; Scott L. DuVall; Dmitry Dymshyts; Sergio Fernández Bertolín; Kristina Fišter; Jill Hardin; Laura Hester; George Hripcsak; Seamus Kent; Sajan Khosla; Spyros Kolovos; Christophe G. Lambert; Johan ver der Lei; Ajit A. Londhe; Kristine E. Lynch; Rupa Makadia; Andrea V. Margulis; Michael E. Matheny; Paras Mehta; Daniel R. Morales; Henry Morgan-Stewart; Mees Mosseveld; Danielle Newby; Fredrik Nyberg; Anna Ostropolets; Rae Woong Park; Albert Prats-Uribe; Gowtham A. Rao; Christian Reich; Jenna Reps; Peter Rijnbeek; Selva Muthu Kumaran Sathappan; Martijn Schuemie; Sarah Seager; Anthony Sena; Azza Shoaibi; Matthew Spotnitz; Marc A. Suchard; Joel Swerdel; Carmen Olga Torre; David Vizcaya; Haini Wen; Marcel de Wilde; Seng Chan You; Lin Zhang; Oleg Zhuk; Patrick Ryan; Daniel Prieto-Alhambra
Title: Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study Document date: 2020_4_10
ID: 2hbcbvt6_28
Snippet: The proposed code lists for the identification of the study population and for the study exposures were created by clinicians with experience in the management of RA using ATLAS , and reviewed by 4 clinicians and 1 epidemiologist (Supplementary Table 2 .1). 39 A total of 16 severe adverse events (SAEs) were analysed. Hospital-based events, not available in primary care records (CPRD, IMRD and SIDIAP), included gastrointestinal bleeding, acute ren.....
Document: The proposed code lists for the identification of the study population and for the study exposures were created by clinicians with experience in the management of RA using ATLAS , and reviewed by 4 clinicians and 1 epidemiologist (Supplementary Table 2 .1). 39 A total of 16 severe adverse events (SAEs) were analysed. Hospital-based events, not available in primary care records (CPRD, IMRD and SIDIAP), included gastrointestinal bleeding, acute renal failure, acute pancreatitis, myocardial infarction, stroke, transient ischaemic attack, and cardiovascular events (composite). Additionally, angina/chest pain, heart failure, cardiac arrhythmia, bradycardia, venous thromboembolism, end stage renal disease, and hepatic failure were analysed from both primary and secondary care data. Mortality outcomes were obtained only from data sources with reliable information on death date (CPRD, IMRD, IPCI, Optum, SIDIAP, VA) and cardiovascular events preceding death records (CPRD, IMRD, Optum, VA), with the former contributing to informing all-cause mortality, and the latter also used to assess to cardiovascular death. All codes for the identification of the 16
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