Author: Tang, Wei; Gartshteyn, Yevgeniya; Guo, Cathy; Chen, Tommy; Giles, Jon; Askanase, Anca
Title: Prophylaxis of COVIDâ€19 with Hydroxychloroquine and Chloroquine Cord-id: xuiqwoao Document date: 2021_3_28
ID: xuiqwoao
Snippet: We read with great interest the paper by Putman et al.(1). The publication reviews data from 45 studies evaluating hydroxychloroquine (HCQ), chloroquine (CQ), anakinra and antiâ€ILâ€6 therapies in COVIDâ€19. Except anakinra, none of the other therapies decreased the risk of death in hospitalized COVIDâ€19 patients. We would like to discuss the evidence evaluating the role of HCQ in the prophylaxis of SARSâ€CoVâ€2 infections. The inâ€vitro antiviral effect of antimalarials suggested a role
Document: We read with great interest the paper by Putman et al.(1). The publication reviews data from 45 studies evaluating hydroxychloroquine (HCQ), chloroquine (CQ), anakinra and antiâ€ILâ€6 therapies in COVIDâ€19. Except anakinra, none of the other therapies decreased the risk of death in hospitalized COVIDâ€19 patients. We would like to discuss the evidence evaluating the role of HCQ in the prophylaxis of SARSâ€CoVâ€2 infections. The inâ€vitro antiviral effect of antimalarials suggested a role in preventing disease progression(2).
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