Author: Bobin Mi; Lang Chen; Adriana C. Panayi; Yuan Xiong; Guohui Liu
Title: Serum Mycoplasma Pneumoniae IgG in COVID-19: A Protective Factor Document date: 2020_4_17
ID: 5vxo6wqt_6
Snippet: Patients with prior exposure to Mycoplasma pneumoniae (IgG positive) showed stronger resistance and better recovery from the SARS-CoV-2 viral infection than patients without exposure. Of particular note, the immune response rendered against the virus was noted to be stronger in the IgG positive group, evident through an overall higher leukocyte count. This can partially be explained by reprogrammed immune cells. 4 Prior evidence has supported tha.....
Document: Patients with prior exposure to Mycoplasma pneumoniae (IgG positive) showed stronger resistance and better recovery from the SARS-CoV-2 viral infection than patients without exposure. Of particular note, the immune response rendered against the virus was noted to be stronger in the IgG positive group, evident through an overall higher leukocyte count. This can partially be explained by reprogrammed immune cells. 4 Prior evidence has supported that when the lungs recover from infection they develop new alveolar macrophage biology, which can protect the lungs of adults against pneumonia. 5 Our retrospective patient review highlighted a similar phenomenon: COVID-19 patients with IgG positivity displayed milder symptoms and rarely experienced severe disease (OR, 2.31; 95% CI, 1.89-3.02). To eliminate the interference of age, we compared the outcomes of elder patients (> 60 years) and Normal ranges for the laboratory values are as follows: white blood-cell count, 3.5-9.5x10 9 /L; hemoglobin,
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