Author: Bainbridge, Emma D; Hsue, Priscilla Y; Esensten, Jonathan H; Lynch, Kara L; Hendrickson, Carolyn M; Doernberg, Sarah B; Fung, Monica; Chin-Hong, Peter; Di Germanio, Clara; Norris, Philip J; Simmons, Graham; Glidden, David V; Luetkemeyer, Anne F
Title: Characteristics of high titer convalescent plasma and antibody dynamics following administration in patients with severe COVID-19 Cord-id: z15os6bn Document date: 2021_7_16
ID: z15os6bn
Snippet: We characterized the antibody composition of COVID-19 convalescent plasma (CCP) and the immunologic responses of hospitalized COVID-19 patients after receiving CCP or non-immune fresh frozen plasma (FFP). Despite selection of CCP with significantly higher total IgG than recipients, neutralizing antibody levels did not differ between donor plasma and CCP recipients.
Document: We characterized the antibody composition of COVID-19 convalescent plasma (CCP) and the immunologic responses of hospitalized COVID-19 patients after receiving CCP or non-immune fresh frozen plasma (FFP). Despite selection of CCP with significantly higher total IgG than recipients, neutralizing antibody levels did not differ between donor plasma and CCP recipients.
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