Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection During Pregnancy In China: A Retrospective Cohort Study

Mingzhu Yin; Lijuan Zhang; Guangtong Deng; Chaofei Han; Minxue Shen; Hongyin Sun; Furong Zeng; Wei Zhang; Lan Chen; Qingqing Luo; Dujuan Yao; Min Wu; Shihuan Yu; Hui Chen; David Baud; Xiang Chen

This study has several limitations. First, we only included the hospitalized patients with laboratory confirmed COVID-19. It could be more methodologically sound to include both pregnant outpatients and inpatients in the analysis to obtain a lees biased estimate comprehensive understanding of the effect of COVID-19 on pregnancy. Second, patient's information such as pregnant outcomes in first and second trimester were incomplete and unavailable at the time of analysis. Third, selection bias might be introduced using 35 non-pregnant patients of reproductive age as control cohort. To clarify, we made a baseline comparison between these 35 non-pregnant patients and all female patients of reproductive age from Hunan province near Wuhan where COVID-19 broke out and found no difference (Table S2) .