Author: Lüsebrink, Jessica; Schildgen, Verena; Schildgen, Oliver
Title: Pooling is an insufficient strategy to avoid healthcare staff to patient transmission of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) Cord-id: ziy5ydti Document date: 2020_11_20
ID: ziy5ydti
Snippet: In order to save the limiting resource of RNA extraction kits we have evaluated the efficacy of pre-extraction sample pooling for SARS-CoV-2 RT-PCR screenings in medical staff. Unfortunately, in contrast to other reports, this strategy results in a loss of sensitivity between 25 to 71% compared to single sample testing, thus making the strategy inappropriate for the current setting.
Document: In order to save the limiting resource of RNA extraction kits we have evaluated the efficacy of pre-extraction sample pooling for SARS-CoV-2 RT-PCR screenings in medical staff. Unfortunately, in contrast to other reports, this strategy results in a loss of sensitivity between 25 to 71% compared to single sample testing, thus making the strategy inappropriate for the current setting.
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