Strong evolutionary convergence of receptor-binding protein spike between COVID-19 and SARS-related coronaviruses

Yonghua Wu

. CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.04.975995 doi: bioRxiv preprint The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.04.975995 doi: bioRxiv preprint Table 1 Positively selected genes identified based on the branch-site model. Only the ω values of the foreground branches are shown. Positive selection sites located in subunit 1 of gene S are shown in grey. Underlining shows positive selected sites located within RBD. Dashes (-) shows alignment gaps in the reference sequence. The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.04.975995 doi: bioRxiv preprint The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.04.975995 doi: bioRxiv preprint . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.04.975995 doi: bioRxiv preprint Table S3 Branches under the positive selection of the S gene. Positive selections are analyzed using branch-site model. For convenience, only the ω values of the foreground branches are shown. Positive selection sites located in subunit 1 of the S gene are shown in grey. Underlining shows positive selected sites located in the RBD.