Author: Tobias Herold; Vindi Jurinovic; Chiara Arnreich; Johannes C Hellmuth; Michael Bergwelt-Baildon; Matthias Klein; Tobias Weinberger
Title: Level of IL-6 predicts respiratory failure in hospitalized symptomatic COVID-19 patients Document date: 2020_4_4
ID: 8udyoutb_9
Snippet: Even though IL-6 levels were significantly elevated in patients requiring ventilation, they are relatively low compared to levels observed in patients with septic shock. 5 Our data suggests that even moderately elevated IL-6 levels above 80pg/ml are sufficient to identify COVID-19 patients with a high risk of respiratory failure. Further studies and larger sample sizes will be needed to validate our findings and possibly determine a more accurate.....
Document: Even though IL-6 levels were significantly elevated in patients requiring ventilation, they are relatively low compared to levels observed in patients with septic shock. 5 Our data suggests that even moderately elevated IL-6 levels above 80pg/ml are sufficient to identify COVID-19 patients with a high risk of respiratory failure. Further studies and larger sample sizes will be needed to validate our findings and possibly determine a more accurate cutoff. To date, it is unclear whether IL-6 merely represents a biomarker or a central pathogenetic element of severe COVID-19 that should be used as a parameter for therapeutic intervention.
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