Selected article for: "virus host and widespread occurrence"

Author: Nagai, Yoshiyuki
Title: Protease-dependent virus tropism and pathogenicity
  • Cord-id: 0hq1ygex
  • Document date: 2003_6_18
  • ID: 0hq1ygex
    Snippet: Viral tissue tropism in a susceptible host is often determined by virus-receptor interactions. Nevertheless, closely related viruses utilizing the same receptor molecules can display striking differences in tropism, or a virus can cause a localized infection despite the widespread occurrence of the receptor. These events are now explained by another mechanism of tropism, in which host proteases play a major role by activating viral fusion glycoproteins.
    Document: Viral tissue tropism in a susceptible host is often determined by virus-receptor interactions. Nevertheless, closely related viruses utilizing the same receptor molecules can display striking differences in tropism, or a virus can cause a localized infection despite the widespread occurrence of the receptor. These events are now explained by another mechanism of tropism, in which host proteases play a major role by activating viral fusion glycoproteins.

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