Author: Sigstad, Eva; Grøholt, Krystyna K; Westerheim, Ola
Title: Subacute thyroiditis after vaccination against SARS-CoV-2./ Subakutt tyreoiditt etter vaksinering mot SARS-CoV-2 Cord-id: 0naq2gxq Document date: 2021_1_1
ID: 0naq2gxq
Snippet: BACKGROUND: Subacute thyroiditis is a clinical condition usually seen 1-2 weeks after a viral infection in the upper respiratory tract, and has also been reported following infection with COVID-19. Cases of subacute thyroiditis following a seasonal influenza vaccination have been described, and recent case reports have reported clinical symptoms and signs typical of subacute thyroiditis following vaccination with mRNA SARS-CoV-2 vaccine. CASE PRESENTATION: A young, healthy female underwent surge
Document: BACKGROUND: Subacute thyroiditis is a clinical condition usually seen 1-2 weeks after a viral infection in the upper respiratory tract, and has also been reported following infection with COVID-19. Cases of subacute thyroiditis following a seasonal influenza vaccination have been described, and recent case reports have reported clinical symptoms and signs typical of subacute thyroiditis following vaccination with mRNA SARS-CoV-2 vaccine. CASE PRESENTATION: A young, healthy female underwent surgery with left-side lobectomy for papillary thyroid carcinoma. Hashimoto's thyroiditis was revealed as an additional histological finding. Six days prior to complementary thyroidectomy of the right lobe the patient received mRNA SARS-CoV-2 vaccine. The histological slides showed features consistent with extensive subacute thyroiditis throughout the entire lobe. INTERPRETATION: As no other aetiology could account for the subacute thyroiditis, the vaccination against COVID-19 is seen as a plausible source.
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