Author: Lucia Grenga; Fabrice Gallais; Olivier Pible; Jean-Charles Gaillard; Duarte Gouveia; Hélène Batina; Niza Bazaline; Sylvie Ruat; Karen Culotta; Guylaine Miotello; Stéphanie Debroas; Marie-Anne Roncato; Gérard Steinmetz; Charlotte Foissard; Anne Desplan; Béatrice Alpha-Bazin; Christine Almunia; Fabienne Gas; Laurent Bellanger; Jean Armengaud
Title: Shotgun proteomics of SARS-CoV-2 infected cells and its application to the optimisation of whole viral particle antigen production for vaccines Document date: 2020_4_17
ID: kd02dehk_34
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.17.046193 doi: bioRxiv preprint detailed information is available regarding virus cell entry, increased understanding of the different steps in the SARS-CoV-2 replication cycle are needed [26] . To our knowledge, this is one of the first attempt to characterize cellular response to infection with SARS-CoV-2 in Vero E6 cells. Interestingly.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.17.046193 doi: bioRxiv preprint detailed information is available regarding virus cell entry, increased understanding of the different steps in the SARS-CoV-2 replication cycle are needed [26] . To our knowledge, this is one of the first attempt to characterize cellular response to infection with SARS-CoV-2 in Vero E6 cells. Interestingly, such proteomics data can be acquired on different cell lines from humans and primates in order to define by comparative proteomics the common mechanisms of cell infection and the mechanisms specific of a given cell line.
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