Author: Lulin Zhou; Zubiao Niu; Xiaoyi Jiang; Zhengrong Zhang; You Zheng; Zhongyi Wang; Yichao Zhu; Lihua Gao; Xiaoning Wang; Qiang Sun
Title: Systemic analysis of tissue cells potentially vulnerable to SARS-CoV-2 infection by the protein-proofed single-cell RNA profiling of ACE2, TMPRSS2 and Furin proteases Document date: 2020_4_10
ID: 3btc31kj_26
Snippet: To obtain comprehensive analysis of the target cells of SARS-CoV-2, we utilized the curated public database to perform scRNA profiling of the ACE2-high and -medium tissues, including lung, heart, kidney, intestinal track (ileum, rectum, colon), stomach, testis, ovary, thyroid and adrenal gland. Plus, we also included liver, the ACE2low organ, into scRNA analysis given its important clinical implications. After quality filtering (see Material and .....
Document: To obtain comprehensive analysis of the target cells of SARS-CoV-2, we utilized the curated public database to perform scRNA profiling of the ACE2-high and -medium tissues, including lung, heart, kidney, intestinal track (ileum, rectum, colon), stomach, testis, ovary, thyroid and adrenal gland. Plus, we also included liver, the ACE2low organ, into scRNA analysis given its important clinical implications. After quality filtering (see Material and methods), We totally obtained 122657 cells and annotated 77 cell types involving respiratory, circulatory, digestive, urinary, reproductive and endocrine systems.
Search related documents:
Co phrase search for related documents- adrenal gland and curated public database: 1
- adrenal gland and public database: 1
- cell type and circulatory endocrine reproductive urinary digestive system: 1
- cell type and colon rectum: 1, 2
- cell type and comprehensive analysis: 1, 2, 3, 4, 5
- cell type and endocrine reproductive urinary digestive system: 1
- cell type and SARS target cell: 1, 2, 3, 4, 5, 6
- circulatory endocrine reproductive urinary digestive system and colon rectum: 1
- circulatory endocrine reproductive urinary digestive system and endocrine reproductive urinary digestive system: 1
- clinical implication and important clinical implication: 1, 2, 3, 4
- colon rectum and endocrine reproductive urinary digestive system: 1
- comprehensive analysis and method material: 1
- comprehensive analysis and public database: 1, 2, 3
- curated public database and public database: 1, 2, 3, 4
Co phrase search for related documents, hyperlinks ordered by date