Selected article for: "dna sequencing and real time"
Author: Maximilian Krause; Adnan M. Niazi; Kornel Labun; Yamila N. Torres Cleuren; Florian S. Müller; Eivind Valen
Title: tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing
  • Document date: 2019_3_25
    • ID: cq7g8azh_16
    Snippet: In conclusion, ONT RNA sequencing offers a new possibility to study poly(A) tail biology, especially by directly associating poly(A) tail length with other RNA features in a transcript isoform-specific manner. tailfindr has proven successful in measuring the poly(A) tail of both RNA and DNA sequencing solely from basecalled raw data, an approach that allows real-time analysis during ONT sequencing. With the application of tailfindr for ONT DNA se.....
    Document: In conclusion, ONT RNA sequencing offers a new possibility to study poly(A) tail biology, especially by directly associating poly(A) tail length with other RNA features in a transcript isoform-specific manner. tailfindr has proven successful in measuring the poly(A) tail of both RNA and DNA sequencing solely from basecalled raw data, an approach that allows real-time analysis during ONT sequencing. With the application of tailfindr for ONT DNA sequencing we allow future development of poly(A)-retaining cDNA sequencing assays that further increase the ability to study poly(A) tail lengths of scarce material.

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