Author: Wenhao Dai; Bing Zhang; Xia-Ming Jiang; Haixia Su; Jian Li; Yao Zhao; Xiong Xie; Zhenming Jin; Jingjing Peng; Fengjiang Liu; Chunpu Li; You Li; Fang Bai; Haofeng Wang; Xi Cheng; Xiaobo Cen; Shulei Hu; Xiuna Yang; Jiang Wang; Xiang Liu; Gengfu Xiao; Hualiang Jiang; Zihe Rao; Leike Zhang; Yechun Xu; Haitao Yang; Hong Liu
Title: Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease Document date: 2020_3_28
ID: b4joa5tx_13
Snippet: In order to elucidate the mechanism of inhibition of SARS-CoV-2 M pro by 11a, we determined the high-resolution crystal structure of this complex at 1.5-Ã… resolution (Table S1 ) 18, 26, 27 . The crystals of M pro -11a belongs to the space group C2 and each author/funder. All rights reserved. No reuse allowed without permission......
Document: In order to elucidate the mechanism of inhibition of SARS-CoV-2 M pro by 11a, we determined the high-resolution crystal structure of this complex at 1.5-Ã… resolution (Table S1 ) 18, 26, 27 . The crystals of M pro -11a belongs to the space group C2 and each author/funder. All rights reserved. No reuse allowed without permission.
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