Selected article for: "affect patient and health care"
Author: Singh, Desh Deepak; Han, Ihn; Choi, Eun-Ha; Yadav, Dharmendra K.
Title: Recent Advances in Pathophysiology, Drug Development and Future Perspectives of SARS-CoV-2
  • Cord-id: 3yyuo8l5
  • Document date: 2020_11_6
    • ID: 3yyuo8l5
    Snippet: The coronavirus (SARS-CoV-2) pandemic is a rapidly transmitting and highly pathogenic disease. The spike protein of SARS-CoV-2 binds to the surface of angiotensin-converting enzyme-2 (ACE2) receptors along the upper respiratory tract and intestinal epithelial cells. SARS-CoV-2 patients develop acute respiratory distress, lymphocytic myocarditis, disseminated intravascular coagulation, lymphocytic infiltration, and other serious complications. A SARS-CoV-2 diagnosis is conducted using quantitativ
    Document: The coronavirus (SARS-CoV-2) pandemic is a rapidly transmitting and highly pathogenic disease. The spike protein of SARS-CoV-2 binds to the surface of angiotensin-converting enzyme-2 (ACE2) receptors along the upper respiratory tract and intestinal epithelial cells. SARS-CoV-2 patients develop acute respiratory distress, lymphocytic myocarditis, disseminated intravascular coagulation, lymphocytic infiltration, and other serious complications. A SARS-CoV-2 diagnosis is conducted using quantitative reverse-transcription PCR and computed tomography (CT) imaging. In addition, IgM or IgG antibodies are used to identify acute and convalescent illness. Recent clinical data have been generated by health workers and researchers and have shown that there is an urgent requirement in the effective clinical and treatment of patients, as well as other developments for dealing with SARS-CoV-2 infection. A broad spectrum of clinical trials of different vaccines and drug treatment has been evaluated for use against SARS-CoV-2. This review includes the emergence of SARS-CoV-2 pneumonia as a way to recognize and eliminate any barriers that affect rapid patient care and public health management against the SARS-CoV-2 epidemic based on the natural history of the disease, its transmission, pathogenesis, immune response, epidemiology, diagnosis, clinical presentation, possible treatment, drug and vaccine development, prevention, and future perspective.

    Search related documents:
    Co phrase search for related documents
    • abdominal pain and active infection: 1, 2, 3
    • abdominal pain and acute phase: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
    • abdominal pain and acute pneumonia: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
    • abdominal pain and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acid detection and active infection: 1, 2, 3, 4, 5, 6, 7, 8
    • acid detection and acute phase: 1, 2, 3
    • acid detection and acute pneumonia: 1, 2, 3, 4, 5
    • acid detection and acute pneumonia cold: 1, 2
    • acid detection and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • active infection and acute phase: 1, 2, 3, 4, 5, 6, 7
    • active infection and acute pneumonia: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • active infection and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • active pocket and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • active site and acute pneumonia: 1, 2, 3
    • active site and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • active site and adjacent residue: 1
    • active site region and acute respiratory syndrome: 1, 2, 3
    • active site residue and acute respiratory syndrome: 1, 2
    • actual sample and acute respiratory syndrome: 1, 2