Selected article for: "nucleotide substitution and reference genome"

Author: Haveri, Anu; Smura, Teemu; Kuivanen, Suvi; Österlund, Pamela; Hepojoki, Jussi; Ikonen, Niina; Pitkäpaasi, Marjaana; Blomqvist, Soile; Rönkkö, Esa; Kantele, Anu; Strandin, Tomas; Kallio-Kokko, Hannimari; Mannonen, Laura; Lappalainen, Maija; Broas, Markku; Jiang, Miao; Siira, Lotta; Salminen, Mika; Puumalainen, Taneli; Sane, Jussi; Melin, Merit; Vapalahti, Olli; Savolainen-Kopra, Carita
Title: Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
  • Cord-id: 4mj7n0ax
  • Document date: 2020_3_19
  • ID: 4mj7n0ax
    Snippet: The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3–23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid
    Document: The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3–23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins.

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