Author: Shen Xu; Lin Fu; Jun Fei; Hui-Xian Xiang; Ying Xiang; Zhu-Xia Tan; Meng-Die Li; Fang-Fang Liu; Ying Li; Ming-Feng Han; Xiu-Yong Li; De-Xin Yu; Hui Zhao; De-Xiang Xu
Title: Acute kidney injury at early stage as a negative prognostic indicator of patients with COVID-19: a hospital-based retrospective analysis Document date: 2020_3_26
ID: b4ay5vyp_29
Snippet: Moreover, the levels of serum urea nitrogen were higher in patients from 50 to 69 years old than those under 50 years old (Table 3 ). In addition, the levels of serum creatinine and uric acid were higher in patients over 70 years old than those under 70 years old (Table 3 ). The effects of comorbidity with either hypertension or diabetes on renal functional indices are shown in Table 4 . The levels of serum creatinine, urea nitrogen and uric acid.....
Document: Moreover, the levels of serum urea nitrogen were higher in patients from 50 to 69 years old than those under 50 years old (Table 3 ). In addition, the levels of serum creatinine and uric acid were higher in patients over 70 years old than those under 70 years old (Table 3 ). The effects of comorbidity with either hypertension or diabetes on renal functional indices are shown in Table 4 . The levels of serum creatinine, urea nitrogen and uric acid were higher in COVID-19 patients with diabetes than those without diabetes. No significant difference on serum creatinine, urea nitrogen and uric acid was observed between COVID-19 patients with hypertension and without hypertension ( (Table 5) . An early study found that SARS patients with AKI were at an increased death risk 17 . In the present study, we analyzed the association of AKI with death risk of COVID-19 patients. Among 56 subjects with AKI on admission, about a third of patients died on mean 10.9 day after hospitalization. The fatality rate was obviously higher among COVID-19 patients with AKI than those without AKI. These results provide evidence that AKI at the early stage elevated death risk of COVID-19 patients.
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