Author: Lulin Zhou; Zubiao Niu; Xiaoyi Jiang; Zhengrong Zhang; You Zheng; Zhongyi Wang; Yichao Zhu; Lihua Gao; Xiaoning Wang; Qiang Sun
Title: Systemic analysis of tissue cells potentially vulnerable to SARS-CoV-2 infection by the protein-proofed single-cell RNA profiling of ACE2, TMPRSS2 and Furin proteases Document date: 2020_4_10
ID: 3btc31kj_38
Snippet: Considering the cell receptor like ACE2 together with the proteases such as TMPRSS2 and Furin are required for the SARS-CoV-2 virus to efficiently infect cells, it is imperative to characterize the co-expression patterns between ACE2 and TMPRSS2 and Furin. Accordingly, we resorted to single-cell transcriptomes to profile their co-expression patterns in the cell types identified......
Document: Considering the cell receptor like ACE2 together with the proteases such as TMPRSS2 and Furin are required for the SARS-CoV-2 virus to efficiently infect cells, it is imperative to characterize the co-expression patterns between ACE2 and TMPRSS2 and Furin. Accordingly, we resorted to single-cell transcriptomes to profile their co-expression patterns in the cell types identified.
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