Biochemical Dynamics and Clinical Features of Novel Corona Virus (2019-nCoV).

Nazir, Taha; Nazir, Saeed Ur Rashid; Sultana, Misbah; Taha, Nida; Riaz, Humayun; Islam, Azharul; Rasheed Kayani, Ruqaiya; Manzoor, Saba

Context The novel Corona Virus (nCoV-19) was initially reported in Wuhan, China during December 2019, and later people with nCoV-19 were identified in different parts of the world. Infected people had shown symptoms resembling pneumonia, but about 50% of patients were asymptomatic. Objective The study intended to examine the data from studies on nCoV-19. Design The research team performed a literature review, searching relevant literature databases. The sources of data included bioRxiv, medRxiv, Google Scholar, Embase, PsychINFO, WanFang Data and PubMed. The search terms were novel Corona Virus, and nCoV-19 structure. Setting The study took place in the main library of the University of Sargodha, Sargodha, Pakistan. Results The study identified 22 studies that had reported and confirmed over 2000 cases of nCoV-19 by January 26, 2020. The studies found that the virus was transmitted through respiratory droplets. The virus has two serotypes, OC43 and 229E. Conclusions No specific curative therapy is available for CoVid-19. However, certain precautionary measures may potentially reduce the transmission, including washing hands, using sanitizers frequently, avoiding public gatherings, and quarantining or isolating patients. This virus has spread globally and immunocompromised individuals, and especially older individuals, are at significant risk. Community and healthcare professionals have a positive role to play in controlling the spread of the disease.